The Nutritional and Metabolic Effects of Boron in Humans and Animals

he studies performed in humans and animals that aimed to obtain further information about the intake and excretion of boron (B) as well as its effects on markers of coronary heart disease. In humans, we have shown that the intake of B is 2.2 mg/day; its urinary excretion is 1.9 mg/day, and there appears to be little intraindividual variation. Supplementation with 10 mg of B/day resulted in the recovery of 84% of the dose in the urine and a significant increase in plasma estradialm concentration, but nom effect on plasma lipoproteins. In rats, increasing intake of B through the drinking water is reflected in the tissue concentrations, in an increase in plasma testosteron and vitamin D, and results in a decrease in HDL cholesterol. It is clear that B has the potential to impact significantly on a number of metabolic processes.

S Samman, MR Naghil, PML Wall, AP Verus. Biol Trace Elem Res 1998;66:227-235.